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sdLDL-C对糖尿病患者早期肾损伤的评估价值.doc


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sdLDL-C对糖尿病患者早期肾损伤的评估价值
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  [摘要] 目的 探讨sdLDL-C对糖尿病患者早期肾损伤的评估价值。 方法 随机收集2017年9月至2019年9月我院糖尿病肾病患者33例作为观察组,同期选取33例健康人群作为对照组。对所有人群进行血糖、糖化血红蛋白(HbA1c)、小而密低密度脂蛋白胆固醇(sdLDL-C)、總胆固醇、三酰甘油、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A、载脂蛋白B、同型半胱氨酸(Hcy)、胱抑素C指标的检查,对比其检查结果,并且计算出尿蛋白排泄率(UAER)以及肾小球滤过率(eGFR),并进行深入分析。 结果 观察组血糖、HbA1c、sdLDL-C、总胆固醇、三酰甘油、LDL-C、载脂蛋白B、Hcy及胱抑素C高于对照组,HDL-C、载脂蛋白A均低于对照组,观察组UAER高于对照组,eGFR低于对照组(P<)。 结论 sdLDL-C在糖尿病患者早期肾损伤的评估中价值显著,适合在临床进行开展和实施。
  [关键词] sdLDL-C;糖尿病;早期肾损伤;评估价值
  [中图分类号] [文献标识码] B [文章编号] 1673-9701(2021)07-0133-03
  The evaluation value of sdLDL-C for early renal injury in diabetic patients
  ZHANG Zhe GE Zixuan
  Department of Laboratory Medicine, the People′s Hospital of Xing′an League in Inner Mongolia Autonomous Region, Ulanhot 137400, China
  [Abstract] Objective To explore the evaluation value of sdLDL-C for early renal injury in diabetic patients. Methods Thirty-three cases were randomLy selected from the diabetic nephropathy patients in our hospital from September 2017 to September 2019 as the subject of this study, named the observation group. And 33 healthy people were selected during the same period as the control group. Blood glucose, glycosylated hemoglobin, small and dense low-density lipoprotein cholesterol, total cholesterol, triacylglycerol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, apolipoprotein A,apolipoprotein B, homocysteine, Cystatin C for all people were detected. The results of the examination were compared, and the urine protein excretion rate and glomerular filtration rate were calculated. An in-depth analysis was conducted. Results The blood glucose, HbA1c, sdLDL-C ,total cholesterol, triacylglycerol, LDL-C, apolipoprotein B, Hcy, and Cystatin C in the observation group were higher than those of the control group. The HDL-C and apolipo

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  • 时间2021-11-20