芪苈强心胶囊联合左西孟旦治疗慢性充血性心力衰竭患者的效果.pdf

第33卷第3期菏泽医学专科学校学报
2021年 JOURNAL OF HEZE MEDICAL COLLEGE 2021
DOI:.1008-
芪苈强心胶囊联合左西孟旦治疗慢性
充血性心力衰竭患者的效果
王玉晓,栾现亭,王艳红
(平顶山市第二人民医院,河南平顶山 467000)
摘要:目的探讨芪苈强心胶囊联合左西孟旦治疗慢性充血性心力衰竭患者的效果。方法选
取慢性充血性心力衰竭患者 113 例,按照随机抽样法分成两组,对照组 56 例给予常规抗心力衰竭加
左西孟旦治疗,观察组 57 例在对照组基础上联合芪苈强心胶囊治疗,1 个月后观察两组患者的临床
疗效、心功能、血管内皮功能、药物安全性。结果观察组治疗后总有效率高于对照组(P<);两组
患者治疗后左室射血分数、心排血量、左室舒张末期容积、左室收缩末期容积值均升高,但观察组升
高幅度高于对照组(P<);两组治疗后 FMD、NMD、峰值流速变化率及 NO 水平均升高,ET-1 水平
均降低,但观察组降低幅度高于对照组(P<);观察组不良反应发生率低于对照组(P<)。结
论芪苈强心胶囊联合左西孟旦治疗慢性充血性心力衰竭效果确切,能够通过益气、活血、利尿等的
作用机制改善患者心功能及血管内皮功能,安全可靠。
关键词:芪苈强心胶囊;左西孟旦;慢性充血性心力衰竭;心功能;血管内皮功能
中图分类号:R24 文献标识码:A 文章编号:1008-4118(2021)03-0053-04
Effect of Qiliqiangxin bined with levosimendan on
patients with chronic congestive heart failure
WANG Yuxiao, LUAN Xianting, WANG Yanhong
(Second People's Hospital of Pingdingshan, Pingdingshan 467000, Henan)
Abstract:Objective To explore the effect of Qiliqiangxin bined with levosimendan in the treatment
of chronic congestive heart failure. Methods 113 cases of patients with chronic congestive heart failure were randomly di⁃
vided into two groups, 56 cases in the control group were given regular anti-heart failure treatment with leosimendan, and
57 cases in the observation group were given Qiliqiangxin capsule on the basis of the control group. After 1 month, the