陈慧芳+刘志军 摘 要 目的:比较分析埃索美拉唑与奥美拉唑治疗胃溃疡的效果。方法:收集2014年3月—2016年1月收治的胃溃疡患者72例,均经胃镜检查确诊。采取数字表法将患者随机分为埃索美拉唑组36例,给予埃索美拉唑20 mg,每天2次;奥美拉唑组36例,给予奥美拉唑20 mg,每天2次,共1个月。观察两组溃疡治疗效果、幽门螺杆菌根除率和患者症状积分改善情况。结果:%(35/36),%(34/36);%(27/36),%(26/36),埃索美拉唑组患者症状积分改善情况优于奥美拉唑组,组间差异有统计学意义(P<)。结论:在治疗胃溃疡中,埃索美拉唑效果更好,可更为快速且有效地清除幽门螺杆菌,在条件允许情况下可优先使用。 关键词 胃溃疡;奥美拉唑;埃索美拉唑 : 文献标志码:A :1006-1533(2017)06-0025-03 Comparative analysis of the effects of esomeprazole and omeprazole in the treatment of gastric ulcer CHEN Huifang, LIU Zhijun (Xinyu Peoples Hospital, Xinyu 338000, Jiangxi Province, China) ABSTRACT Objective: To compare the effects of esomeprazole and omeprazole in the treatment of gastric ulcer. Methods: From March 2014 to January 2016, 72 cases of gastric ulcer treated were collected and diagnosed by endoscopy. With the form of number table method, they were divided into an esomeprazole group who were treated with esomeprazole 20 mg , 2 times a day and an omeprazole group treated with omeprazole 20 mg, 2 times a day for a month. The treatment effect of ulcer, helicobacter pylori eradication rate and improvement of symptom score of the two groups were observed. Results: The total effective rate of ulcer treatment in the esomeprazole group was %(35/36) and the eradication rate of helicobacter pyl