Preface
The real impact of an analytical technique can be assessed using a
combination of several quality indicators, such as the number of
published scientific articles, books and book chapters on the subject,
the availability of instruments in the market and its involvement in
official standard methods, among others. From these indicators, we can
conclude that, capillary electrophoresis (CE) is already consolidated as
a powerful analysis technique that can satisfy a variety of demands for
(bio)chemical information in different social and economic areas. CE is
now a useful alternative to gas and liquid chromatographies and is
increasingly used in routine analytical laboratories for a variety of
reasons such as expeditiousness, peak resolution capability, low sample
volume required, flexibility based on the variety of CE modes, the
feasibility of using homemade approaches, etc. However, we should also
be aware of its limitations, the most obvious being the need for an
efficient sample pretreatment, the low precision due to the potential
lack of representativeness in nanoliter introduction, its lack of
sensitivity, which can be attributed to the low concentration of analyte
reaching the flow-through detector, the difficulty of extrapolating the
results achieved using homemade equipment mercially available
CE instruments used in the laboratory, etc.
The first aim of this book is to show the state of the art of basic CE
using modern approaches, beginning with the fundamentals (chapter
1) and separation modes (chapter 2). The importance of preliminary
operations in CE is shown in two chapters, one devoted to on-line
sample preconcentration techniques (chapter 3) and the other to
coupling flow systems for both homemade mercially available
CE instruments (chapter 4). Because continuous detection is one of the
aspects of CE that need to be improved, many scientists have devoted
much effort to finding better detection alternatives. The second and
more
Analysis And Detection By Capillary Electrophoresis - M Marina, Et Al , (Elsevier, 2005) Ww 来自淘豆网m.daumloan.com转载请标明出处.
