大颗粒透明质酸钠凝胶注射隆鼻的临床观察.doc

大颗粒透明质酸钠凝胶注射隆鼻的临床观察.doc大颗粒透明质酸钠凝胶注射隆鼻的临床观察[ 摘要] 目的:探讨大颗粒透明质酸钠凝胶( hyaluronic acid , HA) 用于注射隆鼻的临床效果。方法: 整理笔者所在医院 2013 年8月-2014 年 6 月应用大颗粒透明质酸钠凝胶注射隆鼻 63例, 分析术后即刻、术后 3个月、 6 个月及 9 个月时患者满意度及并发症情况。结果:术后即刻患者满意度评分为 ,术后 3 个月、 6 个月、 9 个月随访满意度为: 、 、 。术后描述胀疼( 10例)、注射点瘀斑(4例), 均在注射后 1~2 周内自行缓解。注射物明显吸收时间平均为术后 周。结论: 大颗粒 HA注射隆鼻效果满意, 外形维持时间延长, 并发症无增加, 是值得推广的非手术隆鼻方法之一。[ 关键词] 透明质酸;大颗粒;注射;隆鼻术;并发症[ 中图分类号]R622 [ 文献标志码]A[ 文章编号]1008-6455 ( 2015 ) 21-0020-03 Abstract : Objective To investigate the effects of large-gel-particle hyaluronic acid injectable fillers for rhinoplasty. Methods 63 cases injected Biohyalux were reported , from August 2013 to June 2014. In the immediate postoperative , every patient was filled in the Satisfaction every three months. Results Postoperative satisfaction average score was , followed by: , and . Ten cases appeared swelling , and four cases injection site were recovered in1 or2 was obviously absorbed weeks later. Conclusion Large-gel-particle HA injection was applicable to rhinoplasty , and the effect can be maintained for a significant long time. Key words : hyaluronic acid ( HA); large-gel-particle ; injection ; rhinoplasty ; complication 透明质酸钠是人体内分布最广的一种酸性黏多糖, 存在于人体皮肤组织中, 可以吸收约为自身重量一千倍的水分子, 从而维持皮肤弹性和形态。然而人体内多数组织中天然的透明质酸半衰期为 1~ 2d 。因此,要使注射用透明质酸在组织中长期稳定的持续存在, 需要对透明质酸分子结构进行交联加以修饰[1] 。注射用修饰透明质酸钠凝胶-- 润