慢阻肺急性发作期血清炎性指标的变化研究.doc

慢阻肺急性发作期血清炎性指标的变化研究.doc慢阻肺急性发作期血清炎性指标的变化研究[ 摘要] 目的探讨慢性阻塞性肺疾病( COPD )急性发作期患者体内炎性因子的变化及其与疾病发展的关系。方法以该院 201 1年1月― 201 3 年1 月间收治的 80例 COPD 患者为观察组,将该院同期进行的 80 例健康体检者作为对照组, 比较两组患者炎性细胞因子和病情监测指标的差异及相关性。结果观察组患者各炎性细胞因子含量高于对照组,其差异有统计学意义( P< )。在 COPD 患者中, 炎性因子与病情监测指标间呈现线性关系。结论在 COPD 急性发作期患者体内各炎性因子含量是上升的, 且其于 COPD 的病情发展程度有关,可作为临床诊断与监测指标,具有积极意义。[ 关键词] 慢性阻塞性肺疾病;急性发作期;炎性因子[ 中图分类号] R245 [ 文献标识码]A[ 文章编号] 1674-0742 ( 2014 ) 01(a) -0011-02 Study on the Changes of Serum Inflammatory Cytokines in the Acute Phase of COPD ZHAO Yonggang Emergency Department , Zhangjiagang First People's Hospital , Zhangjiagang , Jiangsu Province , 215600 , China [Abstract] Objective To investigate the correlation between the changes of inflammatory cytokines of patients with COPD during the acute phase of COPD and the development of the disease. Methods 80 patients with COPD admitted in our hospital from January , 2011 to January , 2013 were selected as the observation group , and 80 healthy subjects underwent health examination in our hospital during the same period were selected as the control group. The difference and correlation of level of inflammatory cytokines and the monitoring indicators of COPD pared between the two groups. Results The level of inflammatory cytokines in the observation group were higher t han that in the control group , the difference was statistically significant ( P< ). In COPD patients , there was a line