有限元分析和骨密度比较分析股骨近端切除的力学分析.pdf

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Langton, Christian and Pisharody, S. and Keyak, J. H. (2009) Comparison of 3D finite
element analysis derived stiffness and BMD to determine the failure load of the excised
proximal femur. Medical Engineering & Physics, 31(6). pp. 668-672.





© Copyright 2009 Elsevier Ltd on behalf of IPEM.
Comparison of 3D finite element analysis derived stiffness and BMD to determine the
failure load of the excised proximal femur
Langton C M1, Pisharody S2, Keyak J H3

1Medical Physics, Queensland University of Technology, Brisbane, Australia
2Department puter Science, University of Hull, Hull, UK
3Department of Orthopaedic Surgery, University of California, Irvine, USA


Corresponding Author:
Professor C M Langton, Medical Physics, Queensland University of Technology, Brisbane
4001, Queensland, Australia
Tel: +61 7 31382002
Email: christian.******@



1
Abstract
Introduction: Bone mineral density (BMD) is currently the preferred surrogate for bone
strength in clinical practice. Finite element analysis (FEA) is puter simulation technique
that can predict the deformation of a structure when a load is applied, providing a measure of
stiffness (N mm−1). Finite element analysis of X-ray images (3D-FEXI) is a FEA technique
whose analysis is derived from a single 2D radiographic image.
Methods: 18 excised human femora had previously been puted
Tomography scanned, from which 2D BMD-equivalent radiographic images were derived,
and mechanically tested to failure in a stance loading configuration. A 3D proximal femur
shape was generated from each 2D radiographic image and used to construct 3D-FEA
models.
Results: The coefficient of determination (R2%) to predict failure load was % for BMD
and % for 3D-FEXI.
Conclusions: This ex-vivo study demonstrates that 3D-FEXI derived from a conventional 2D
radiographic image has