82 四川生理科学杂志 2021, 43(1) E and NGB expression in patients with severe craniocerebral injury after surgery. Methods: According to the random number table method, 128 patients with severe craniocerebral injury in our hospital from June 2018 to October 2019 were divided into the control group and the study group (n=64). All patients were treated with modified decompressive craniectomy. The control group was treated with hyperbaric oxygen (cabin pressure was set at MPa), and the study group was treated with ginkgo leaf extract and Damo injection 15 times on the basis of hyperbaric oxygen The treatment lasted for 3 months. The clinical efficacy of the two groups was evaluated after 3 months of treatment; Glasgow Coma Scale (GCS), Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MCE) were used before and after 3 months of treatment The levels of serum neuron specific enolase (NSE) and Neuroglobin (NGB) were measured by enzyme-linked immunosorbent assay before and 3 months after treatment, and malondialdehyde (MDA) and superoxide dismutase (superoxide dismutase) were measured by post immunoturbidimetry SOD content. Results: Compared with before treatment, G