孟鲁司特钠对反复呼吸道感染患儿炎症相关指标水平的影响.doc

孟鲁司特钠对反复呼吸道感染患儿炎症相关指标水平的影响
[摘要]目的 研究孟魯司特钠对反复呼吸道感染患儿炎症相关指标水平的影响。方法 选取2017年9月~2018年7月我院收治的80例反复呼吸道感染的患儿作为研究对象,采用随机数in-5 [IL-5] and interferon-α [IFN-α]) and total effective rate of treatment were compared between the two groups. Results After 2 months of treatment, the levels of IgA and IgG in the experimental group were higher than those in the control group, the IgE level was lower than that in the control group, and the differences were statistically significant (P<). The levels of neutrophils and eosinophils in the experimental group were lower than those in the control group, the levels of lymphocytes and mononuclear macrophages were higher than those in the control group, and the differences were statistically significant (P<). The levels of IL-2 and IFN-γ in the experimental group were higher than those in the control group, the levels of IL-4, IL-5 and IFN-α were lower than those in the control group, and the differences were statistically significant (P<). The total effective rate of treatment in the experimental group was %, which was higher than % in the control group, and the difference was statistically significant (P<). Conclusion The application of Montelukast Sodium in the treatment of children with recurrent respiratory infection can improve the total effective rate of clinical treatment and improve the clinical indicators of inflammation in children. It is worthy of clinical application. [Key words] Montelukast Sodium; Children with recurrent respiratory infection; Inflammation-related indicators; Clinical efficacy
反復呼吸道感染的好发人群是2~6岁的儿童,大多患儿的免疫功能较低下,在临床上属于由支原体感染引起的常见呼吸系统疾病,患儿的病程长,发作次数频繁,支原体在进入呼吸道后和神经氨酸受体结合,在呼吸道黏膜上皮细胞的位置聚集,产生有害的物质并导致慢性消耗,影响其他功能脏器的活动,严重影响了患儿的生活质量[1-2]。因此,治疗反复呼吸道感染的目的是控制感染和增强免疫力。本研究选取我院呼吸内科治疗的反复呼吸道感染的80例患儿作为研究对象,旨在研究孟鲁司特钠对反复呼吸道感染患儿炎症相关指标水平的影响,现报道如下。
1资料与方法

选取2017年9月~2018年7月我院呼吸内科收治的80例反复呼吸道感染的患儿作为研究对象,采用随机数字表法将所有纳入研究的患儿分为对照组和实验组,每组各40例。对照组中,男25例,女15例;年龄2~12岁,平均(±)岁;每年发作