傅健介绍——皮肌炎的临床特点.ppt

皮肌炎的临床特点皮肌炎是一种累及皮肤和肌肉的非感染性炎性疾病。女:男=2:1;40~ 60岁多见傅健医生 1 Evaluation only. Evaluation only. Created with Client Profile . Created with Client Profile . Copyright 2004-2011 Aspose Pty Ltd. Copyright 2004-2011 Aspose Pty Ltd. 1. 皮肌炎型; 2. 儿童皮肌炎型; 3. 皮肌炎伴恶性肿瘤型; 4. 皮肌炎伴其它结缔组织病型; (肌炎型) 根据临床特点分为五型: 2 Evaluation only. Evaluation only. Created with Client Profile . Created with Client Profile . Copyright 2004-2011 Aspose Pty Ltd. Copyright 2004-2011 Aspose Pty Ltd. 病因及发病机理:::、过度劳累:诱发皮肌炎 3 Evaluation only. Evaluation only. Created with Client Profile . Created with Client Profile . Copyright 2004-2011 Aspose Pty Ltd. Copyright 2004-2011 Aspose Pty Ltd. 临床表现: 多为逐渐发病,少数为急性发作,迅速发展。以皮肤和肌肉病变为主,但二者发生时间及严重程度并不平行 4 Evaluation only. Evaluation only. Created with Client Profile . Created with Client Profile . Copyright 2004-2011 Aspose Pty Ltd. Copyright 2004-2011 Aspose Pty Ltd. 临床表现: 一. 皮肤损害: 1. 双上眼睑为中心的水肿性暗紫红斑,可扩展至额、颧颊、耳部、上胸部( V 型)。重者可发展至四肢伸侧。 2. 常有毛细血管扩张,色沉或色减和毳毛增多、增长。 5 Evaluation only. Evaluation only. Created with Client Profile . Created with Client Profile . Copyright 2004-2011 Aspose Pty Ltd. Copyright 2004-2011 Aspose Pty Ltd. 临床表现: 四肢大关节伸侧出现对称分布红斑,伴有糠状鳞屑。有些慢性病例躯干部可出现相同皮损,皮肤干燥呈皮肤异色病样皮疹。可伴有萎缩。一般无痒感等自觉症状 6 Evaluation only. Evaluation only. Created with Client Profile . Created with Client Profile . Copyright 2004-2011 Aspose Pty Ltd. Copyright 2004-2011 Aspose Pty Ltd. 临床表现: 另一特征性皮疹为 Gottron 丘疹( Gottron papule ),为指关节伸侧紫红色斑或扁平隆起性丘疹,复以小鳞屑, 一般发生在疾病的中后期, 见于 1/3 的病人。皮损消退后留有萎缩,毛细血管扩张和色减斑 7 Evaluation only. Evaluation only. Created with