不同发病年龄的精神分裂症患者临床特征分析.doc

临床医学论文-不同发病年龄的精神分裂症患者临床特征分析
              作者:颉瑞王刚平张永录裴根祥
【关键词】  发病年龄;精神分裂症;临床特征
【摘要】目的   探讨不同发病年龄精神分裂症患者的临床特征。方法   将276例精神分裂症患者分为早发组(年龄<25a)172例和晚发组(年龄≥25a)104例;采用自编项目调查表对入组患者的临床资料进行回顾性调查分析。结果   早发组家族史、城乡及第1胎次均与晚发组有显著性差异(P<)。早发组思维贫乏、情感淡漠及行为紊乱较晚发组多见;晚发组幻听及其他妄想较早发组多见。结论   不同发病年龄的精神分裂症患者存在遗传与临床特征方面的差异。
【关键词】发病年龄;精神分裂症;临床特征
Analyses on clinical features of schizophrenics with different onset ages.
【Abstract】 Objective   To explore the clinical features of schizophrenics with different onset ages. Methods   276 schizophrenics were divided into early(aged <25 years, n=172) and late(aged ≥25 years, n=104) onset groups; clinical data were retrospectively analyzed with selfmade questionnaire. Results   There were significant differences in familial history, city or village and the 1st birth order between the early and late onset group (P<).The poverty of thought ,apathy and behavior disorder were moner in the early than in the late group (P<).Auditory hallucination and other delusion were moner in the late than in the early group(P<). Conclusion   There are differences in heredity and clinical features of schizophrenics with different onset ages.
【Keywords】 Onset age ;schizophrenia; clinical feature
近年国内外对精神分裂症的病因、发病机制、症状及预后方面研究较多。国外有学者认为精神分裂症在不同发病年龄之间存在着遗传和临床特征的差异[1]。为研究不同发病年龄的精神分裂症患者的临床特征,本文对不同发病年龄精神分裂症患者的临床资料进行了回顾性比较研究,现将结果报告如下。
1 资料与方法
资料   调查对象