胸腰椎脊柱结核.doc

胸腰椎脊柱结核常彦海刘军凌鸣范亚一刘时璋李勇祁洁刘宗智关键词:脊柱结核;胸腰椎;化疗;脊柱融合术;内固定器 Short-course chemotherapy and bone grafting with internal fixation for the treatment of thoracic and lumbar spinal tuberculosis. Chang Yan-hai, Liu jun, Ling ming, et al.( Department of Orthopaedics , Shan xi Provincial People ’ s Hospital , Shaanxi Xi,an 710068 ) Abstract: Objective To evaluate the clinical efficacy of short-course chemotherapy and anterir surgical method or anterior-posterior method for the treatment of thoracic and lum bar spinal tuberculosis. Methods From 2002 ~ 2007, 38 patients with spinal tuberculosis were treated with chemotherapy including 4 kinds medicine for 3 months,and postoperatively 3 kinds medicine was continual used for 6 months. One-staged anterior lesion debridement, bone grafting and internal fixation were performed on 21 patients, combined anterior debridement and bone grafting with posterior transpedicular instrumentation were performed on 17 observed indices included the cure of tuberculosis, bone-healing rate and recovery of neurological function. Results 35 cases were followed-up for average years (from to3 years). Spinal pletely cured. No significant systemic and plications were found. The patient wit h spinal neurological deficits recovered,the grafted bone pletely, and the time was between 4~7 months. No loose and break of the internal fixation was found. Conc