白蛋白发酵.ppt

Bioprocess automation
Karl Bayer (IAM国际气象协会)
Otto Doblhoff-Dier (IAM, Igeneon, Wien)
Robert Mikler (ISE Wien)
LV Automatisierung von Bioprozessen
Automatisierung von Bioprozessen
Ziel: Einsatz von Automatiserungssystemen zur Führung von Bioprozessen
LV Automatisierung von Bioprozessen
Bioprocess(生物加工) automation
key elements of the bioprocess
contribution(贡献) of automation  to processing
LV Automatisierung von Bioprozessen
PROCESS AUTOMATION 生产过程自动化
Definitions定义
Process: Integrated(完整的) system by which the transformation(转换) and/or transport of materials原料, energy and/or information is plished
Process control 过程控制Automatic control of a process, in which puter system is used to regulate(调节) the usually continuous operations or processes
Process monitoring工艺过程的监控:acquisition(获得) of key variables变量
Automation: Sequence of operations running without the interaction of man没有人的互动运行的操作序列. Advanced level of automation is robotics 机器人技术
Goal: optimal(最佳的) utilisation(利用) of biological 生物学的systems
biosynthesis (生物合成)
transformation (转化)
degradation (降解)
Impact(作用) of process control in bioprocessing生物工艺
Efficiency (yield 收益) of a bioprocess is determined确定的 by
performance性能 of the cell factory
environmental parameters环境参数监测
Main tasks主要任务:
maintenance of process conditions维修工艺条件 by monitoring and control监控和控制
documentation
PROCESS CONTROL and AUTOMATION过程控制与自动化
Reasons for increasing need for automation and use puters in bioprocessing需要自动化和计算机的使用生物敷料的原因Need for accelerated(加速的) process development and increased efficiency and economies of production processes
process level过程层
process regimes(体系) became far plex and sophisticated复杂的高级的 . 例如(batch  fed batch(流加式操作)
continuous increase of variables to be monitored要监视的变量的连续增加
plexity of variables日益复杂的变量
level of quality(质量) management
demands (需要) related to quality management increased dramatically显著地增加(hidden plant, makes approx大约. 35% (up to 70%) of costs成本)
increased demands on