太赫兹生物效应的原理和应用 李鼎.pdf

: .
光学与光电技 DNA 去
甲基等，为太赫兹技术的生物医学应用奠定了基础。最后总结太赫兹生物效应
的研究现状，对该领域的重点研究方向和可能的突破点进行分析展望。
关键词：太赫兹；太赫兹光谱；太赫兹成像；太赫兹医学；太赫兹生物效
应；

Principles and applications of terahertz biological effects
Li Ding and Zhang Yan*
(Department of Physics, Capital Normal University, Beijing 100089)
*Email: ******@

Abstract: Terahertz technology has been developed rapidly over the past few
decades. As a powerful tool for charactering biomacromolecules, terahertz
spectroscopy and imaging technologies have been demonstrated their broad prospects
in diagnostic and clinical medicine. The specific components of biological samples can
be quantitatively analyzed by a terahertz spectroscopy, and similarly, the spatial
distribution of the components measured in samples can be detected with terahertz
imaging systems. This paper reviews some representative in the fields of terahertzdiagnostic medicine based on the types of terahertz optical systems, some investigations
on terahertz biological effects are introduced from the level of biological individuals,
tissues, cells, and biological macromolecules. Although this field is still in the trial and
preliminary exploration stage, there are many pioneering researches with great potential
have been proposed, such as terahertz-assisted targeted drug transmembrane transport
and terahertz cancer cell DNA demethylation. Finally, the research status of terahertz
biological effects is summarized and the key directions and possible breakthroughs in
this field ar