高通量血液透析对慢性肾衰竭患者血清氨基酸谱影响.docx

significantly higher

than

that of the normal control(:t: ,P
<)。(2)Both

One

time CHD and HFD had

no

significant

influence

on

serum
amino acids concentrations

fP>).The

influence of HFD and CHD

01"1
seram
albumin:CHD could significantly increase the blood level of albumin g/L
vs
:<),and

I-IFD could also

significantly

increase the blood level
of albumin(: g/L

vs

,78

g/L,P<).(3)After
3 months of HFD,
the patients’serum amino acids profile was improved

serunl EAA、
BCAA、AAA and TAA levels showed

no

significant difference

between the

patients
and

the healthy

control(P>).It Was

found that

there Was

no
significant
improvement in the previously abnormal decreasing ratio of BCAA]AAA and in the
previously
abnormal

increasing ratio of Phe/Tyr,Gly/Ser(P>),pared
with the healthy controlled group,Was statistically 3 months ofHFD,
the

blood
albumin

level

before

dialysis

was
increased(
-a:,L,P=).
Conclusions

1 In spite that the blood albumin level of some CHD patients Was
normal,their

seruul

amino acids level Was

the

free amino
acids
of hemodialysis patients is helpful to assess their nutrition

status,and

instructive to
treat The patients

suffering from the chronic renal failure were tolerant
of HFD,and there was

no

significant
change in their serl/m amino acids 3
months of continuous HFD could improve the patients
amino

acids profile,increase
the blood level of albumin,but failed to correct
abnormal
amino acids level which
previously existed.
【Key words]—flux:amino acids;albumin
7
前言
营养不良是长期依赖普通血液透析(CHD)的慢性肾衰竭患者的常见并发症,
与患者的死亡率和生活质量的下降密切相关。慢性肾衰竭患者由于尿毒症本身的