ICU患者输注不同储存期红细胞悬液后的疗效观察.docx

该【ICU患者输注不同储存期红细胞悬液后的疗效观察 】是由【wz_198613】上传分享，文档一共【2】页，该文档可以免费在线阅读，需要了解更多关于【ICU患者输注不同储存期红细胞悬液后的疗效观察 】的内容，可以使用淘豆网的站内搜索功能，选择自己适合的文档，以下文字是截取该文章内的部分文字，如需要获得完整电子版，请下载此文档到您的设备，方便您编辑和打印。ICU患者输注不同储存期红细胞悬液后的疗效观察
Introduction
Red blood cells (RBCs) are one of the essential components in the treatment of critically ill patients in the intensive care unit (ICU). In the past, the storage duration of blood was typically three to four weeks, but current practice allows for extended storage of up to six weeks. However, concerns have been raised regarding the potential negative effects of prolonged storage on transfusion outcomes. This study aims to observe the efficacy of RBC suspension at different storage periods in ICU patients.
Methods
This study included 100 adult ICU patients who required RBC transfusion. The patients were randomly divided into two groups based on the storage period of the RBC suspension: Group A received RBC suspension stored for less than three weeks, while Group B received RBC suspension stored for more than three weeks. The two groups were compared in terms of their clinical characteristics, transfusion outcomes, and incidence of adverse events.
Results
There were no significant differences in the baseline characteristics, including age, gender, and underlying diseases, between the two groups. The transfusion recovery rate was significantly higher in Group A than in Group B (p < ). The hemoglobin increment was also significantly higher in Group A than in Group B (p < ). The incidence of adverse events, such as allergic reactions and transfusion-related acute lung injury (TRALI), was higher in Group B than in Group A, although the difference was not statistically significant.
Conclusion
The findings of this study suggest that the efficacy of RBC suspension in critically ill ICU patients may be affected by the storage period. RBC suspension stored for less than three weeks appears to be more effective in transfusion outcomes, including the recovery rate and hemoglobin increment, than RBC suspension stored for more than three weeks. In addition, the incidence of adverse events, such as allergic reactions and TRALI, may be lower with RBC suspension stored for a shorter period. These findings provide essential information for clinical decision-making regarding the choice of RBC suspension in critically ill ICU patients. However, further studies are needed to confirm these results and evaluate the long-term effects of extended storage periods on transfusion outcomes.