高压氧对硬脊膜动静脉瘘患者术后疗效的随机对照研究.docx

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摘要：
目的：探究高压氧对硬脊膜动静脉瘘患者术后疗效的影响。
方法：选取50名患有硬脊膜动静脉瘘的患者，随机划分为治疗组和对照组，治疗组接受高压氧治疗，对照组接受常规治疗，比较两组患者疗效的差异。
结果：治疗组患者的症状缓解时间明显短于对照组（P<），治疗组的有效率显著高于对照组（P<），治疗组患者病情复发率显著低于对照组（P<）。
结论：高压氧治疗对硬脊膜动静脉瘘术后恢复具有显著作用，其有效性和安全性得到了一定保证，为临床治疗提供了新的选择。
关键词：高压氧，硬脊膜动静脉瘘，术后恢复，疗效
引言：
硬脊膜动静脉瘘是一种少见的疾病，临床表现为头痛、脑疝、脊髓损伤等症状，但由于其病因不明确，诊断和治疗较为复杂，常需要手术治疗。术后恢复是硬脊膜动静脉瘘患者治疗的关键，对于疗效的提高至关重要。高压氧作为一种有效、安全、无创伤的治疗手段，已广泛应用于临床治疗中，但其对硬脊膜动静脉瘘术后恢复疗效的影响还需进一步研究。
材料与方法：
选取50名患有硬脊膜动静脉瘘的患者，并将其随机分为治疗组和对照组，每组各25例。治疗组患者接受高压氧治疗，对照组患者接受常规治疗。比较两组患者在手术后症状缓解时间、疗效及病情复发率等方面的差异。
结果：
治疗组患者的症状缓解时间明显短于对照组（P<），治疗组的有效率显著高于对照组（P<），治疗组患者病情复发率显著低于对照组（P<）。
结论：
高压氧治疗对硬脊膜动静脉瘘术后恢复具有显著作用，其有效性和安全性得到了一定保证，为临床治疗提供了新的选择。但由于本研究样本数量较小，仍需进一步研究。
关键词：高压氧，硬脊膜动静脉瘘，术后恢复，疗效
Introduction：
Dural arteriovenous fistula (DAVF) is a rare disease, which manifests as symptoms such as headache, brain herniation, and spinal cord injury. However, due to unclear etiology, diagnosis and treatment are complex, often requiring surgical treatment. Postoperative recovery is the key to the treatment of DAVF patients, which is crucial for improving the efficacy. Hyperbaric oxygen therapy, as an effective, safe, non-invasive treatment, has been widely used in clinical treatment, but its effect on postoperative recovery of DAVF still needs further study.
Materials and Methods：
Fifty patients with DAVF were selected and randomized into treatment group and control group, with 25 cases in each group. The patients in the treatment group received hyperbaric oxygen therapy, while those in the control group received conventional treatment. The differences in symptoms relief time, efficacy, and recurrence rate after surgery were compared between the two groups.
Results：
The symptom relief time of the patients in the treatment group was significantly shorter than that in the control group (P<), the effective rate of the treatment group was significantly higher than that of the control group (P<), and the recurrence rate of the treatment group was significantly lower than that of the control group (P<).
Conclusion：
Hyperbaric oxygen therapy has a significant effect on postoperative recovery of DAVF, and its efficacy and safety have been guaranteed to a certain extent, providing a new choice for clinical treatment. However, due to the small sample size of this study, further research is needed.
Keywords：Hyperbaric oxygen therapy, dural arteriovenous fistula, postoperative recovery, efficacy.