NAME:Ranitidine hydrochloride
The molecular formula is C 13H22N4O3S•HCl
Clinical Pharmacology
Ranitidine is petitive, reversible inhibitor of the action of histamine at the histamine H2-receptors, including receptors on the gastric cells.
Indications
(Oral) Short-term treatment of active duodenal ulcer (DU) and benign gastric ulcer (GU). Maintenance therapy for DU and GU at reduced dosage after healing of acute ulcers. Treatment of pathological hypersecretory conditions and GERD. Treatment and maintenance of healing of erosive esophagitis.
General Dosing
For Adult:
Usual:50mg q6-8h as intermittent bolus/infusion or continuous IV infusion Max: 400mg/day
For Children
Gastroesophageal Reflux Disease/Erosive Esophagitis
1 Month-16 Years:5-10mg/kg/day given as 2 divided doses
Duodenal
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