Abstract:AIM To study the expression of calcitonin gene-related peptide(CGRP)in spinal cord after irradiation on in-jured sciatic nerve of rat by He-Ne laser with output power Injured sciatic nerves,made in96SD rats,were irradiated by He-Ne changes of CGRP in spinal cord were immunohistochemically ┐SULTS Expression of CGRP increased in spinal cord on the first day after injury of sciatic expression of CGRP in second and fourth week was observed in laser irradi-ation pared to control positive sub-stance was mainly found in motor neuron in anterior horn and sensory nerve fiber in posterior eighth week,CGRP remained a high expression in both groups,and showed no significant Expression of CGRP in spinal cord can be changed by He-Ne laser irradiation with power output of10mW on injured sciatic nerve in -Ne laser irradiation can promote nerve regeneration.
