,(Tg)基因活性的改变对甲状腺疾病临床诊断的价值,(“I治疗21倒,手术治疗9倒),桥本甲状腺炎89倒(甲状腺功能正常59倒,甲状腺功能减低30例),甲亢211倒(未治疗40例,抗甲状腺药物治疗中130倒,”I治疗后41倒)结果:330例甲状腺疾病患者Tg基因位毂脆性表选频率皆有不同程度的改变,”I治疗的21倒甲状腺癌和41倒甲亢病人,Fra8q22明显高于未经”I治疗的甲状腺癌和甲亢病人(,P<0叭).结论:”I辐射导致基困结掏的损伤,,LiJianguo,ChenXianyu,-sltyMedicalScience,theFirstspital,Chongqing630042AbstractPURPOSETostudythevaLueofthyroglobuItn(T)—centrationandgeneactivitywasstudiedin330thyroidpatients;includingthyroidcarcinoma30(Itherapy21andoperation9),(thyroidfunctionnormaL59andhypo30)andhyperthyroidism211(untreated40,antithyroiddrugtherapy130,”Itherapy41).RESULTSTherewerechangeswithvariousdegreeaboutfragiLesitesexpresstrequeneeands[gnifi——thyroidismtreatedbyI,Fra8q22marktyincreasedthanthatofuntreatedgroups(t=,P<).~hyroglobulinGenes人甲状腺球蛋白(HTg)是由甲状腺滤泡上皮细胞合成的一种含碘蛋白质,,在某些甲状腺病变时,固甲状腺功能异常或甲状腺组织细胞的损伤
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