IntracellularpatternrecognitionreceptorsinthehostresponseEtienneMeylan,JürgTschopp,MichaelKarinVol442-6,39-43July2006,,Toll-likereceptorsareaclassofmembranereceptorsthatsenseextracellularmicrobesandtriggeranti-,intracellularmicrobialsensorshavealsobeenidentified,includingNOD-likereceptors(nucleotide-bindingoligomerizationdomain)andthehelicase(解旋酶)-domain-containingantiviralproteinsRIG-,aswellasnon-microbial,dangersignals,,(PRRs):anisms—viruses,bacteria,fungiandparasites—-associatedmolecularpatterns(PAMPs)ponentsofbacterialandfungalcellwalls,Flagellar(鞭毛)proteins,,
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