重庆大学硕士学位论文中文摘要载药量(%),.(CH2)3NH2载药体系均能实现缓释。。关键词:,氢氯噻嗪,孔径,氨丙基,,precisioncontrolled·releaseorreleaseondemand,toextendthedrugtime,,binedwithpharmacy,materialsscience,·To文舰mmeidealreleasebehavior,thecarriermaterialshouldhavetheappropriatephysicalandchemicalproperties,theresponsetoenvironment,patibility,(),thestableframeworkstructure,easymodification,largers耐如eare钆nonbiologicalactivity,non-toxic,,,largersurfacearea(>1000m2/g),,Silicashowshightoleranceinvivo,andinfactitiscurrentlybeingusedinsomepharmaceuticalformulationsandMCM.-,-termadministrationbecauseofthesmallerdosageofthehydrochlorothiazide(onedayneedstwoorthreeadministrations).。themesoporousmolecularsieveMCM·4issynthesizedbymicrowaveradiationmethodusingCetyltrimethylammoniumBromideassurfactantandsodiumsilicateassilicasource,diureticdmgsisassembledintothepasswayofmesoporousmolecularsieveMCM一41bytheimpregnation,theMCM-41anddrug勰semblie
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