包皮环切能防止HIV感染.ppt

包皮环切能防止HIV感染?彭弋峰皖南医学院弋矶山医院性医学科yifengpeng@包皮环切术的历史包皮环切仪式在西非已沿袭了五千年以上。在中东也至少有三千年的历史。EARLIEST DEPEICTION OF MALE CIRCUMCISIONEARLIEST DEPEICTION OF MALE CIRCUMCISIONTomb of Tomb of AnkhmahorAnkhmahor, Architect to the Pharaoh , Architect to the Pharaoh SaqqaraSaqqara, Egypt 2300 ., Egypt 2300 ChristBorn December 25th AD0001As a Jew, circumcised on the 8th day of life January 1stTHE FEAST OF THE CIRCUMSISIONProfessor . ShortMUHAMMADBorn 570 a, Saudi ArabiaCIRCUMCISEDProfessor . Short19世纪末及20世纪初的美国和加拿大,包皮环切是用来代表一种医药文化。到70年代早期,加拿大约有40%、美国约有89%的新生儿施行包皮环切手术。中国包皮环切百分率?Cir-cum-Cir-cum-cisioncision::The surgical removal of the The surgical removal of the skinskinthat covers the tip of the that covers the tip of the penispenis..Definition of CircumcisionDefinition of Circumcision??Simple ? Simple ? ?? Easy ? Easy ? ??Just cutting the foreskin?Just cutting the foreskin?Oh, dear, es your surgeon , dear, es your surgeon ,全世界大约四分之一的男人做过包皮环切术,大多集中于美国、加拿大、中东和亚洲穆斯林国家以及大部分非洲国家。包皮环切的益处(1)?排除包茎的危险?阴茎皮肤感染的风险减少三倍?婴儿尿道感染的风险减少十倍?患阴茎癌的风险降低二十倍以上?患前列腺癌的风险降低二倍?经性交感染HIV的风险减少三倍包皮环切的益处(2)?对其他STD的感染,如乳头状病毒、梅毒、软下疳,也有实质性的保护?女性性伴侣患由人类乳头状病毒所致的宫颈癌及感染衣原体的危险减少五倍?多数妇女更喜欢环切后的阴茎外观,更乐意与之性活动?性功能与未环切者一样好或更好男性包皮环切显著地降低男性在阴茎-阴道性交时获得性HIV感染风险包皮环切术与艾滋病毒传播风险包皮环切术与艾滋病毒传播风险Patterson BK, Patterson BK, LandayLanday A, Siegel JN, et al. Susceptibility to human immunodeficiency virus-1 infection of A, Siegel JN, et al. Susceptibility to human immunodeficiency virus-1 infection of human foreskin and cervical tissue grown in human foreskin and cervical tissue grown in explantexplant culture. culture. Am J Am J PatholPathol. 2002 Sep;161(3):867-73. . 2002 Sep;161(3):867-73. SzaboSzabo R, Short RV. How does male circumcision protect against HIV infection? R, Short RV. How does male circumcision protect against HIV infection? BMJBMJ. 2000 Jun . 2000 Jun 10;320(7249):1592-4. 10;320(7249):1592-4. Weiss HA, Thomas SL, Weiss HA, Thomas SL, MunabiMunabi SK, Hayes RJ. Male circumcision