左旋甲状腺素治疗亚临床甲减、临床甲减的疗效观察.doc

左旋甲状腺素治疗亚临床甲减、临床甲减的疗效观察[摘要]目的探讨左旋甲状腺素治疗亚临床甲减、临床甲减的临床疗效及对患者血脂水平的影响。方法选取144例甲状腺功能减退患儿作为研究对象,按照就诊顺序将其随机分为两组,每组为72例,两组患者均给予降糖、控压、扩张冠状动脉等常规对症治疗,观察组给予左旋甲状腺素钠,比较两组患者治疗前后甲状腺激素水平和血脂水平变化。结果观察组治疗后FT3、FT4和TSH水平分别为(+)pmol/L、(±)pmol/L和(+)mIU/L,均较治疗前和对照组明显改善;而TC和TG水平分别为(±)mmol/L和(±0・32)mmol/L,均较治疗前和对照组显著降低,且两组比较差异均具有统计学意义(P〈)。结论左旋甲状腺素治疗亚临床甲减、临床甲减疗效显著,可明显改善患者甲状腺功能,降低血脂水平,具有较好的临床应用和推广价值。[关键词]左旋甲状腺索;亚临床甲减;临床甲减[中图分类号][文献标识码]B[文章编号]2095-0616(2015)02-51-03Observationoftheclinicalefficacyofsubclinicalhypothyroidism,,Children'sHospitaiofZhengzhouCity,Zhengzhou450000,China;,Children"sHospitalofZhengzhouCity,Zhengzhou450000,China[Abstract]ObjectiveToobservetheclinicalefficacyandtheeffectiononbloodlipidlevelofsubclinicalhypothyroidism,,ordingtotheorderoftreatment,,pressurecontrol,expansionofcoronaryarteryandotherconventionalsymptomatictreatment,,FT3,FT4andTSHlevelsoftheobservationgroupwere(±)pmol/L,(±)pmol/Land(±)mlU/L,significantlyimprovedtha