Vocal Cord Medialization by Transcutaneous Injection of…：声带内移经皮注射….pdf

Vocal Cord Medialization by Transcutaneous Injection of Calcium Hydroxylapatite *Richard G. M. Hughes and ?Murray Morrison Stafford, United Kingdom, and Vancouver, British Columbia, Canada Summary: Transcutaneous vocal cord augmentation has increasingly e the method of choice when treating causes of vocal cord insuf?ciency. Many substances have panied this technique, but they all have problems. One newersubstance is calcium hydroxylapatite (CaHA). CaHAmayproduce fewer problems and offer a longer-lasting treatment. Twenty-one patients were treated in the Paci?c Voice Clinic with trancutaneous injection of CaHA for vocal cord paralysis (n ?19) and vocal scarring (n ?2). Maximum phonation time (MPT) was the measure of vocal performance. An improvement was seen in 20 patients with the MPT, who improved from seconds before treatment to seconds at posttreatment of 3 months (n ?15). This improvement was maintained at 6 months (MPT ?12 seconds, n ?12). Follow-up was plete because of the terminal nature of some diagnoses and the large geographical area covered by the clinic. Three subjects had submucosal injection of CaHA (two resolving spontaneously). Two other patients had extrusion of the material. With short-term and medial-term follow-up on a small group of patients, encouraging results were seen with transcutaneous injection of CaHA for vocal cord augmentation. Key Words: