佝偻病手足抽搐症.pptx

What happened to these children ?
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First thorough account of rickets
Francis Glisson(1650)
Martins e Silva J. Acta Reumatol Port,2007. 32:205.
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Mellanby Edward(1918)
Isolation of the antiricketic factor from liver oil
Mellanby E. Br Med J, 1924 , 24: 895
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Adolf windaus (1922)
Synthetically prepare vitamin D3
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“ no more campaign on rickets”
In the 1970s
Veena Bahl. Nutrition & Food Science, 1993, 81 :2
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Rowe PM. Lancet,2001,357:1100
In the 2000s
“I think this is a major unrecognized epidemic in the United States. It affects children and adults of all ages, all races, and both sexes. It’s very significant. ”
“Vitamin D deficiency symptoms in children have long been overlooked.”
The Lancet: “re-emergence of rickets”
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Rickets of vitamin D deficiency
营养性维生素D缺乏性佝偻病
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To be familiar with its pathology, diagnosis and differential diagnosis
Teaching aims
To master its etiology,clinical manifestations, treatment and prevention of Rickets
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Definition
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What is Rickets?
Mineralization:矿化 Osteoid:骨样组织 Osteomalacia:骨软化症
Rickets is the term signifying a failure in mineralization of growing bone or osteoid tissue due to deficiency of vitamin D
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