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BLAT−−The BLAST-Like Alignment Tool
W. James Kent
Genome Res. 2002 12: 656-664
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Cold Spring Harbor Laboratory Press
Downloaded from on January 12, 2010 - Published by Cold Spring Harbor Laboratory Press
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BLAT—The BLAST-Like Alignment Tool
W. James Kent
Department of Biology and Center for Molecular Biology of RNA, University of California, Santa Cruz,
Santa Cruz, California 95064, USA
Analyzing vertebrate genomes requires rapid mRNA/DNA and cross-species protein alignments. A new tool,
BLAT, is more accurate and 500 times faster than popular existing tools for mRNA/DNA alignments and 50
times faster for protein alignments at sensitivity settings typically used when comparing vertebrate se
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