LES的临床意义.doc

食管下括约肌长度测定的临床意义北京医科大学学报 1999 年第 1 期第 31卷论著作者:邹磊蒋绚赵景涛单位:北京医科大学人民医院消化内科,北京 100044 关键词:食管胃接合处;解剖学和组织学;胃食管反流;病理学;压力摘要目的: 明确食管及其下括约肌长度在胃食管反流疾病中的变化及临床意义。方法: 用灌注式多导测压系统对正常组 63 例受试者及胃食管反流组 53 例病人进行食管压力测定。结果: 正常人各年龄组食管下段括约肌长度差异无显著性; 胃食管反流性疾病组食管下段括约肌长度及腹段下括约肌长度均显著下降;正常组与胃食管反流性疾病组身高与食管长度的相关系数分别为 r 1 = , r 2 = 。结论: 食管下括约肌长度在抗反流中起到重要作用,其在正常人群中不随年龄而变化;胃食管反流性疾病患者未伴食管长度缩短、上提。中国图书资料分类法分类号 R573 Clinical study on measurement of length of lower esophageal sphincter ZOU Lei , JIANG Xuan , ZHAO Jing-Tao (Department of Gastroenterology, People's Hospital, Beijing Medical University, Beijing 100044) MeSH Esophagogastric junction/anat Gastroesophageal reflux/pathol Pressure ABSTRACT Objective : To investigate the changes of esophageal and lower esophageal sphincter length in gastroesophageal reflux disease (GERD). Methods : PC Polygraf system was used to measure esophageal intraluminal pressure on 63 normal cases and 53 GERD cases with four channel tube assembly. Results : In normal cases the length of lower esophageal sphincter in different age groups had no significant difference. In GERD group the length of lower esophageal sphincter and intra abdominal sphincter obviously decreased. The related coefficient between esophageal length and body length in normal and GERD groups was and , respectively. Conclusion : The length of lower esophageal sphincter was important in anti-reflu