Bioinformatics In Microbial Biotechnology – A Mini Review.pdf

Microbial Cell Factories BioMed Central
Review Open Access
Bioinformatics in microbial biotechnology – a mini review
Arvind K Bansal*
Address: Department puter Science, Kent State University, Kent, OH 44242, USA
Email: Arvind K Bansal* - ******@
* Corresponding author
Published: 28 June 2005 Received: 01 May 2005
Accepted: 28 June 2005
Microbial Cell Factories 2005, 4:19 doi:-2859-4-19
This article is available from: tent/4/1/19
© 2005 Bansal; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the mons Attribution License (/licenses/by/),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The revolutionary growth in putation speed and memory storage capability has fueled a new era in the
analysis of biological data. Hundreds of microbial genomes and many eukaryotic genomes including a cleaner draft
of human genome have been sequenced raising the expectation of better control of anisms. The goals
are as lofty as the development of rational drugs and antimicrobial agents, development of new enhanced bacterial
strains for bioremediation and pollution control, development of better and easy to administer ines, the
development of protein biomarkers for various bacterial diseases, and better understanding of host-bacteria
interaction to prevent bacterial infections. In the last decade the development of many new bioinformatics
techniques and integrated databases has facilitated the realization of these goals. Current research in
bioinformatics can be classified into: (i) genomics – sequencing parative study of genomes to identify gene
and genome functionality, (ii) proteomics – identification and characterization of protein related properties and
reconstruction of metabolic and regulatory pathways, (iii) cell visualization and simulation to study and model cell
behavior, and (iv) appl