【摘要】 目的 分析他克莫司软膏联合润肤剂在儿童特应性皮炎治疗中的应用效果。方法 收集2017 年8 月至2018年8 月我院收治的特应性皮炎患儿80 例,随机平分为观察组和对照组,对照组患儿在常规对皮损部位进行清理后,使用他克莫司软膏进行治疗,观察组患儿首先使用润肤剂对皮损部位进行清理,而后使用他克莫司软膏进行治疗,比较两组患儿治疗效果、治疗前后症状严总程度和不良反应发生率。结果 %, %,P<;观察组患儿治疗后2周和4 周EASI评分均明显低于对照组,P<;观察组不良反应发生率明显低于对照组,P<。结论 他克莫司软膏联合润肤剂可有效提高儿童特应性皮炎的治疗效果,对于改善患儿症状、减少不良反应均具有积极作用,值得推广应用。 【关键词】特应性皮炎;润肤剂;他克莫司软膏 【Abstract 】 objective to analyze the effect of tacrolimus ointment combined with emollient in the treatment of children atopic dermatitis. Method collected in August 2017 to August 2018 children with atopic dermatitis of our hospital 80 cases, randomly split into observation group and control group, control group with vitiligo patches after cleaning simple use of tacrolimus ointment treatment, observation group with using emollients used after cleaning areas of tacrolimus ointment treatment, compare the treatment effect in two groups of children, symptoms before and after the treatment of severe degree and incidence of adverse reactions. Results the effective rate was % in the observation group and % in the control group, P<. Observation group 2 and 4 weeks after treatment in children with EASI scores were significantly lower than the control group, P < ; The incidence of adverse reactions in the observation