盐酸舍曲林联合依木萨克治疗早泄的临床研究梁国庆 1,陈春雷 1,陈伟杰 1,李铮 2 (,上海200071;,上海200135) 【摘要】目的:研究盐酸舍曲林联合中药依木萨克片治疗早泄的可行性及疗效。方法:门诊收集无器质性疾病的早泄患者100例,随机分成2组,每组50例。A组患者A盐酸舍曲林50mg/d(性生活前4~6小时服用);B组患者盐酸舍曲林50mg/d(性生活前4~6小时服用) ,连续服用4周。比较2组治疗前后的平均阴道内射精潜伏期(IELT)、配偶性生活满意度评分、观察治疗期间的不良反应。结果:%,%。两组患者的IELT及其配偶性交满意度评分方面在治疗后较治疗前均显著增加, 差异具有统计学意义(P<)。B组患者的IELT和配偶性交满意度评分则显著高于A组, 差异具有统计学意义(P<)。B组用药患者出现不良反应6例,与A组比较差异无统计学意义。结论:盐酸舍曲林联合依木萨克治疗早泄在延长IELT和改善配偶性交满意度方面具有更好的疗效。【关键词】早泄;盐酸舍曲林;伊木萨克片;药物疗效【Abstract】Objective:To evaluatethe clinical effectof sertraline and Yimusake tablet ontreatment ofpremature ejaculation(PE).Methods:Totally of one hundred PE patients wererandomlydivided intotwo equalgroups (n=50). Thepatients in Group A were treated withsertraline50mg/dfor 4weeks, while in Group B with sertratine 50mg/dandYimusaketablet for and after the treatment, the mean intravaginalejaculatorylatency time(IELT), the intercourse satisfactionandthe drug adverse effectof patients were :.The total rate of effectiveness was %in group A and %in groupB. The mean IELT andtheintercourse satisfaction after the treatment were improved significantly in two groups than that of before treatment(P<).The IELT andtheintercourse satisfaction in group B were increased
