妇科感染病(Female Genital System Infection)-张喜.ppt

Female Genital System Infection Women ’ s Hospital, School of Medicine Zhejiang University Prof. Lin Jun Natural resistance to infections ? vulvae ? vagina ? cervix ? endometrium ? fallopian tubes ? immune system Vulvovaginal infection Self-purification of vagina (阴道自净作用) estrogen → vaginal epithelium → glycogen ↓ lactic acid ↓ normal vaginal flora ← - (chiefly lactobacilli) Vulvovaginal infection Ecosystem of vagina (阴道生态系统) Balance lactobacilli PH estrogen Vulvovaginal infection Trichomonal Vaginitis ? Pathogen : Trichomonas vaginalis ? Forms of transmission: ? Sexual transmission ? Indirect contact transmission Trichomonal Vaginitis ? Clinical findings : ⒈ Increase in vaginal discharge ? greenish ? extremely frothy ? foul-smelling ⒉ Vulvar pruritus Trichomonal Vaginitis ? Clinical findings : ⒊ Examination ? vaginal erythema ? so-called strawberry spots on cervix ? typical discharge Trichomonal Vaginitis ? Diagnosis : Demonstration of trichomonad in vaginal discharge Trichomonal Vaginitis ? Treatment :? systemic therapy ? metronidazole ? vagina local therapy ? treat partners simultaneously with intercourse avoided ? patients with pregnancy: metronidazole, systemic therapy Vulvovaginal infection Vulvovaginal candidiasis ( VVC ) 75% of women will experience an episode ? Pathogen : Candida ? candida albicans( 白假丝酵母菌) 80%-90% ? candida albicans frequently inhabits the mouth, throat, large intestine, and vagina normally.