牛布鲁氏菌病.docx

牛布鲁氏菌病
（病）Bovine Brucellosis （Bangs）
Prepared by: Dr. Terry Hunt
Translated by Dr. Ren Xiaoling
Cause & Pathogenesisally third trimester abortionsStillborn calvesRetained placenta and metritis Decreased milk production（子宫炎），一般可能无症状
Cows may not be sick unless secondary problems (metritis) •公牛有睾丸炎，精囊腺炎和附睾炎(生殖道)
Orchitis, seminal vesiculitis and epididymitis in bulls (reproductive tract)
•从乳房淋巴结或公牛感染的睾丸培养细菌Culture organism from mammary lymph nodes or infected testis of bulls•其他原因引起牛的后期流产Other causes of late term abortion in cattle
诊断
Diagnosis
•后期流产的胎儿
•坏死性胎盘炎
•从胎盘分离细菌
Aborted late term fetuses
Necrotizing placentitis
Isolation of the organism from placenta
鉴别诊断
Differential Diagnosis
实验室和病理学诊断 Laboratory and Pathology 筛选试验Screening tests确诊试验Confirmatory tests•不选择治疗，预防和扑灭是目标Treatment is not an option as prevention and eradication is the goal •扑杀感染牛〜Slaughter infected cattle
•全乳环状试验 •缓冲平板抗原试验
•ELISA试验
Milk ring test
Buffered plate antigen test
ELISA
•补体结合试验 •间接酶免疫测定 治疗
Complement fixation
Indirect enzyme immunoassay
Treatment
后遗症
•隐性携带者 •子宫炎
•跛行
•不孕
Sequelae
Inapparent carriers
Mastitis
Lameness
Infertility
防^Prevention & Control•许多发展中国家己经扑灭了本病
Most developed countries have eradicated the disease•在扑灭疫病的初期，扑杀、注射疫苗是最重要的
Initially, a vaccination program is important in the eradication of the disease 免疫程序Vaccination Program•用19株疫苗接种2-8月龄的小母牛
V