正丁基锂拔氢.pdf

Tetrahedron Letters, Vol. 37, No. 42, pp. 7503-7506, 1996
Pergamon Copyright © 1996 Published by Elsevier Science Ltd
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Straightforward Synthesis of 4-Formyl- and 4,4'-Diformyl-2,2'-Bipyridines:
Access to New Dialkenyl Substituted Bipyridyl Ligands.
Philippe Dupau, Thierry Renouard and Hubert Le Bozec*
Laboratoire de Chimie de anique, associ~ RS, Universit~ de Rennes 1, Campus de
Beaulieu, 35042 Rennes Cedex, France
Abstract. 4-Formyl- and 4,4'-diformyl-2,2'-bipyridineshave been prepared in two steps and in 52-71%
overall yields v/a enaminationof the corresponding4-methyl and 4,4'-dimethyl-2,2'-bipyridinederivatives.
The synthesisof two new 4,4'-dialkenyl-2,2'-bipyridyl ligands is also described.
Copyright © 1996 Published by Elsevier Science Ltd
4,4'-Diformyl-2,2'-bipyridinessuch as 3a and 3b are useful synthons for the elaboration of functionalized
bipyridines and oligobipyridines. However their syntheses involve several steps and are low ,2 In the
course of our research on the synthesis of 4,4'-dialkenyl-2,2'-plexes for nonlinear optics 3,4
we have e interested in developing a more convenient method for the preparation of 3a and 3b. Here we
describe a two-steps and good yield procedure to mono and diformyl-2,2'-bipyridines