2021 3 23 101 11 Natl Med J China, March 23, 2021, Vol. 101, No. 11 813 中华医学杂志 年 56±16 s 50 ） ，使用氟马西尼拮抗后，平均苏醒时间为（ ） 。 例患者中，发生呼吸抑制、头晕头痛和乏 1 力的患者各 例。结论 基于甲苯磺酸瑞马唑仑的中深度镇静策略可以有效地用于纤支镜检查和治 μg/kg ED50 mg/kg 疗。甲苯磺酸瑞马唑仑复合 舒芬太尼用于纤支镜检查中深度镇静的 为 ； ED95 mg/kg 为 。 【关键词】 支气管镜； 药物剂量计算； 中深度镇静； 甲苯磺酸瑞马唑仑 Observation of effective dosage of remimazolam tosilate used for moderate‑to‑deep sedation in fiberoptic bronchoscopy Jia Zhen, Ren Lixia, Fan Yetie, Tan Zhiming Department of Anesthesiology, Affiliated Hainan Cancer Hospital of Hainan Medical College, Hai Kou 570100, China Corresponding author: Tan Zhiming, Email: ******@ 【Abstract】 Objective To estimate the safety and efficacy of remimazolam tosilate used for moderate‑to‑deep sedation in fiberoptic bronchoscopy with its 50% effective dosage (ED50) and 95% effective dosage (ED95) calculated. Methods A total of 50 patients aged from 18 to 65 years Ⅰ Ⅱ and classified as Class or according to the American Society of Anesthesiologists (ASA) Classification who underwent fiberoptic br
