《红斑狼疮》课件.ppt

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幽默来自智慧,恶语来自无能
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Pathology(病理)
Pathologicalmorphologyvariesdependingonthecondition,location,largechanges.
Thereareseveralcommontypes.
Vascularlesionsformofnecrotizingvasculitisofsmallvessels,includingsmallarteriesorarterioles.
Patientswithkidneydiseasewillalsohavediaeaseoftherenalglomerulusandrenaltubulesandinterstitialandbloodvessels.
Cardiacabnormalitiesincludingpericarditis,myocarditis,heartvalvesandendocardialdisease.
Pathologicalchangesofskinincludingepidermal(表皮的)atrophy(萎缩),necrosis(坏死)oftheskinulcers(溃疡)andedema(水肿).
Diffuselesions(弥漫性病变)ofthenervoussystemconsistoffewernervecells,smallvesselvasculitis,smallinfarction(梗塞),necrosisandhemorrhage(出血).
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Pathogeny(病因)
TheexactcauseofLupusErythematosushasnotbeenfound,whichisthesameasotherautoimmunediseases.
Environmentalpollutioncanalsocausethisdiaeasewhichshouldbepayattentionto.
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Geneticfactors
Infectionfactors
Endocrinefactors
Environmentalfactors
Otherfactors
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Clinicalsymptoms
anddetectionmethods
clinical
symptoms
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Raynaud'sphenomenon
(雷诺现象)
Dermalpathology
(皮肤病理)
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Blooddisorder(血液病变)
Organdamage
Lymphaticsystem
Fever
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Arthritis
(关节炎)
Oralornasal
pharyngealulcer
Infection
(传染性)
clinical
symptoms
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Dermalpathology皮肤病理
Facialbutterflyerythema(面部蝶形红斑);discerythema(盘形红斑);dermatitiscausehairloss
,suddenlyoccurredinreferstosmallarteryspasm.
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Raynaud'sphenomenon(雷诺现象)
Blooddisorder(血液病变)
Allkindsofbloodcellsarereducing,additionnally,patientsmaysufferfromvasculitis
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Organdamage
Patientsmaysufferfromheartdamage,lungdamage,braindamage,gastrointestinaldamage(消化道损害),withlupusnephritis(狼疮性肾炎)andeyelesions
clinical
symptoms
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Lymphaticsystem
About50%ofSLEpatientswithlocalorsystemiclymphnodeenlargement,inneck,armpits,jawsswelling,whicharesoftandnotenderness.
Patientstendtobeimmunologicdysfunction,whosebodycanproducemanykindsofsubstances,asaheatsourceandmakethebodyheat.
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Fever
Arthritis(关节炎)
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Oralornasalpharyngealulcer
(口腔及鼻咽部溃疡)
clinical
symptoms
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Infection(传染性)???
Althoughtheincidenceofsleisfarhigherinourcountrythanwesterncountries,,alotofpeopledon',theywillwanttoknowwhetheritisinfectious?Theanswerisno,'simmunetolerance,makingthebody',study,andparticipateintheactivitiesofsocietylikethenormal
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Treatmentandpreventionof
lupuserythematosus,LE
Treament
SLE
系统性红斑狼疮
CLE
n,
皮肤型红斑狼疮