MDSMPN分类与诊断MDS-MPN2 PPT课件.ppt

MDSMPN分类与诊断MDS-MPN2_PPT课件兰州大学第二医院张连生
2009-10-30 于杭州
MDS/MPN的分类与诊断
2008 WHO Classification scheme for myeloid neoplasms
MDS/MPN分类
myelomonocytic leukemia (CMML)
慢性粒-单核细胞白血病
myelomonocytic leukemia (JMML)
幼年型粒-单核细胞白血病
CML, BCR-ABL1–(aCML, BCR-ABL1–)
不典型慢性髓系白血病 BCR-ABL1基因阴性
unclassifiable (MDS/MPN-U)
骨髓增生异常综合征/骨髓增殖性肿瘤不能分类
category, refractory anemia with ringed sideroblasts and thrombocytosis (RARS-T)
暂定类-难治性贫血有环状鉄粒幼细胞板血小板增多
Definition
MDS/MPN(D)
de novo myeloid neoplasms that exhibit hybrid dysplastic and proliferative features at presentation
MDS
MDS/MPN
MPN
Cytopenia
Dyserythropoiesis
Dysgranulopoiesis
Dysmegakaryopoiesis
Monocytosis
Granulocytosis
Thrombocytosis
Eosinophilia
Mastocytosis
Erythroc