内科医学毕业论文--呼吸内科病房院内肺部真菌感染的临床分析.doc

内科医学毕业论文
呼吸内科病房院内肺部真菌感染的临床分析
【摘要】目的探讨上海中医药大学附属普陀医院呼吸内科病房患者肺部真菌感染发病的易患因素、临床特征和治疗。方法采用回顾性调查方法对2005年6月~2006年12月收住内科的经微生物检查证实54例继发肺部真菌感染的患者进行分析。结果在呼吸内科病房中,院内肺部真菌感染发生率为38%,慢性阻塞性肺疾病(518%)是继发院内肺部真菌感染最常见的基础疾病,长期使用广谱抗生素(963%)、低蛋白血症(593%)、长期使用糖皮质激素(333%)及合并糖尿病是主要易患因素。肺部真菌感染的临床表现无特异性,确诊需结合痰培养,组织病理学和临床表现来确定,病原菌以白色假丝酵母菌(611%)为主,氟康唑治疗有效率922%。结论院内肺部真菌是呼吸系统疾病继发感染的重要病原体,而白色假丝酵母菌是院内肺部真菌感染的主要致病菌,有效的抗真菌治疗外,积极的综合治疗有助于提高真菌感染的治愈率。
【关键词】肺;院内感染;真菌
analysis on ial pulmonary fungal infection in respiratory department ward
cai zhu-ying,tang ji-hong,wang lei,et of respiratory diseases,putuo hospital,shanghai university of tcm,shanghai 200062,china
[abstract] objective to study the susceptible factors,clinical features and treatments of ial pulmonary fungal infection in the ward of respiratory the chart files of 54 patients with ial pulmonary fungal infection admitted from june 2005 to december 2006 in the ward 本文来自文秘114 保留此标记。 of respiratory department were the incidence rate of ial pulmonary fungal infection was 38%.copd(518%)was the main predisposing disease,and candidiasis(611%) was the mon pathogen. the main susceptible factors associated with ial pulmonary fungal infection are long-term use of broad-spectrum antibiotics(963%),hypoalbuminemia(593%),long-term use of adrenocortical steroid(333%),and diabetes is no spe