17520例宫颈液基细胞学的组织病理学分析 (作者:___________单位: ___________邮编: ___________) 作者:孔慧祥,谢江南,朱洪波,邹顺 【摘要】目的探讨宫颈液基细胞学与组织病理学诊断的符合情况,评估液基细胞学技术及TBS诊断系统在妇科普查宫颈疾病中的价值。方法对17520例患者做Thin Prep膜式薄层液基细胞学检查,结果异常者依次做5%醋酸宫颈染色,肉眼观察并摄影,阴道镜检查及宫颈多点活检病理组织学检查。细胞学诊断采用TBS(2001)分级报告系统,阳性诊断包括意义不明的不典型鳞状细胞(ASCUS)及以上标本;且所有ASCUS以上病变的患者全部有病理组织学诊断结果,并对两者进行了对照分析。结果 17520份宫颈细胞学检查与组织病理学对照结果显示:4例鳞状细胞癌(SCC)均符合,高级别鳞状上皮内病变(HSIL)%(160/169),低级别鳞状上皮内病变(LSIL)%(78/98)。细胞学TBS分级与组织病理学呈正相关。结论应用液基细胞学制片方法、准确掌握TBS的诊断标准可确保宫颈细胞学检查的准确性,并可及早发现宫颈早期病变。 【关键词】液基细胞学;TBS;宫颈上皮内瘤样病变;宫颈肿瘤;对比研究 【Abstract】 Objective To study the diagnostic correspondence of liquid-based cervix cytology and histopathology and assess the value of liquid-based cytology technology and TBS system in the diagnosis of cervix Thin Prep liquid-based cytological examination was used in 17520 patients. 5% acetic acid stain was used in abnormal patients. Visual observation, photography, colposcopy and cervical biopsy were used. TBS (2001) report grading system was used in cytological diagnosis including the positive diagnosis of atypical squamous cells (ASCUS) or more specimens. Results 17520 copies of the results of cervical cytology and histopathology results showed: 4 cases of squamous cell carcinoma (SCC) were in line with the high-grade squamous intraepithelial lesions (HSIL) % (160/169), a low-level squamous intraepithelial lesion (LSIL) wa
