46例ICU机械通气患者并发下呼吸道感染病原菌和药敏分析.doc

46例ICU机械通气患者并发下呼吸道感染病原菌和药敏分析
【关键词】下呼吸道感染
摘要:目的分析ICU机械通气患者并发下呼吸道院内感染病原学构成和耐药情况。方法采用回顾性调查方法,对46例接受机械通气并发下呼吸道感染患者的下呼吸道分泌物中的致病菌及药敏结果进行分析。用无菌吸痰管或纤支镜采集下呼吸道分泌物,按常规方法送检培养。结果检出致病菌84 株,其中G-菌62株(%),G+菌16株(%),真菌6株(%)。前4位致病菌分别为铜绿假单胞菌22株(%),不动杆菌属16株(%),肠杆菌属12株(%),金黄色葡萄球菌10株(占1191%)。铜绿假单胞菌、不动杆菌属和肠杆菌属均对亚胺培南最为敏感,葡萄球菌对万古霉素最为敏感,上述菌株多重耐药现象严重。结论 ICU机械通气患者并发下呼吸道院内感染病原菌以G-菌为主,其药敏试验呈现多重耐药,临床应引起足够重视,开展细菌耐药监测并合理使用抗生素。
关键词:机械通气;下呼吸道感染;病原菌; ICU; 药敏试验
Abstract: Objective To analyze the pathogens of lower respiratory tract infection in patients receiving mechanical ventilation in ICU and the pathogens drug resistance. Methods The pathogens and the drug resistance of lower respiratory tract infection in 46 patients receiving mechanical ventilation and plicated in ICU were investigated. Results 84 strains pathogens were isolated by bacterial culture. The ratio of the gramnegative bacteria to 62 strains (%),and the grampositive bacteria was 16 strains (%),the fungi was 6 strains (%).Among pathogens the mon were (22 strains),Acinebacter(16strains),Enterobacteriaceae(12stains),(10strains).Imipenem and Cilastatin Sodium was the most sensitive drug for ,Acinebacter,Enterobacteriaceae. And ycin Hydrochloride was the most for drugresistancemultiple to antimicrobial agents is serious. Conclusions Gramnegative bact