Adults---------------------DOSAGEFORMSANDSTRENGTHSExtended-ReleaseTablets:50mg,150mg,200mg,300mg,®(quetiapinefumarateextended-releasetablets,:1997WARNING:INCREASEDMORTALITYINELDERLYPATIENTSWITHDEMENTIA-RELATEDPSYCHOSIS;•Elderlypatientswithdementia-relatedpsychosistreatedwithSEROQUELXRisnotapprovedforelderlypatientswithdementia-relatedpsychosis.•Increasedriskofsuicidalthoughtsandbehaviorinchildren,adolescentsandyoungadultstakingantidepressants.•Monitorforworseningandemergenceofsuicidalthoughtsandbehaviors.--------------------------RECENTMAJORCHANGES-------------------------WarningsandPrecautions,CerebrovascularAdverseReactions,IncludingStroke,inElderlyPatientswithDementia-RelatedPsychosis(---4/2013---------------------------INDICATIONSANDUSAGE-------------------------SEROQUELXRisanatypicalantipsychoticindicatedforthetreatmentof:•Schizophrenia•BipolarIdisorder,manicormixedepisodes(•Bipolardisorder,depressiveepisodes•Majordepressivedisorder,adjunctivetherapywithantidepressants----------------------DOSAGEANDADMINISTRATION---------------------•Swallowtabletswholeanddonotsplit,cheworcrush•Takewithoutfoodorwithalightmeal((•Administeroncedaily,preferablyintheevening•GeriatricUse:Consideralowerstartingdose(50mg/day,slowertitration,andcarefulmonitoringduringtheinitialdosingperiodintheelderly.(,•HepaticImpairment:Lowerstartingdose(50mg/dayandslowertitrationmaybeneeded(,,DoseDoseSchizophrenia-Adults(-800mg/day800mg/daySchizophrenia-Adolescents(13to17years50mg/day400-800mg/day800mg/daymanicormixed-Acutemonotherapyoradjuncttolithiumordivalproex-AdultsBipolarIDisorder,manicAcutemonotherapyChildrenandAdolescents(10to17years50mg/day400-600mg/day600mg/dayDepressiveEpisodes-AdultsDisorder,AdjunctiveTherapyw
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