64例进展型脑梗死纳洛酮治疗临床分析.doc

临床医学论文-64例进展型脑梗死纳洛酮治疗临床分析
                  作者:刘丹平,宗媛,赵文彩,姬新才 
【关键词】  盐酸纳洛酮;进展型脑梗死;胞二磷胆碱
[摘要] 目的:探讨盐酸纳洛酮对进展型脑梗死的临床疗效。方法:选择128例进展型脑梗死患者分为两组,其中64例应用纳洛酮,64例对照组应用胞二磷胆碱,疗程15 d,治疗前后分别行神经功能缺损评分,疗程结束后行临床疗效评定。结果:治疗组治疗后神经功能缺损评分较对照组改善明显,临床疗效优于对照组,治疗中未出现明显不良反应。结论:纳洛酮治疗急性进展型脑梗死能有效抑制梗死区扩大及防止病灶进展,起效快,疗效好且无不良反应。
[关键词] 盐酸纳洛酮;进展型脑梗死;胞二磷胆碱
Efficacy of Naloxone in Acute Cerebral Infarction in 64 Patients
Abstract:Objective The objective of this study is to evaluate the clinical of Naloxone in acute cerebral 128 acute cerebral infarction patient is ized into treated group(64 patients,treated with naloxone for 15 days)and control group(64 patients,treated with citicoline for 15 days).nerve malfunction is evcluated before and after treatment in each Nerve mallfunction and clinical efficavy treated group is significantly higher than the control group,and there is no significant difference inside effect rate of each Naloxone is safe of efficant in trenting acute cerebral infarction.
Key words:Naloxone;Nerve malfunction;Citicoline
进展性脑梗死为病情在数小时至数天内逐渐加重,系局灶性神经功能缺失症状逐渐进展,呈阶梯式加重,可持续数天,常规治疗效果欠佳。我们对2000年至2004年经陕西省人民医院急诊内科应用盐酸纳洛酮治疗的64例进展型脑梗死与用胞二磷胆碱治疗的病例进行对比,现报告如下。
1 资料与方法
一般资料
128例住院进展型脑梗死患者均符合1995年全国第四届脑血管病学术会议所确定的诊断标准,并满足下列条件:急性脑梗死,发病1 h~4 h,病情进展;首次发病或发病后未留下神经功能缺损症状;瘫痪肢体肌力<4级;头颅CT检查排除脑出血。将患者随即分为两组,治疗组64例,男40例,女24例,年龄40岁~82岁,平均(60
±1