心肌炎综述.pdf

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7). However,
These bone marrow-derived cells promote not only tissue injury in the short detection of N14 CD3- and/or CD68-
term but also angiogenesis and collagen deposition in the long term. Thus, expressing cells per millimeter squared
they are critically involved in the typical tissue fibrosis, which evolves in the by immunohistochemistry provides a
dilating ventricle during the process of pathologic remodeling. Recent more sensitive diagnostic criterion.
From a clinical perspective, many myo-
findings suggest that heart-infiltrating monocyte-like cells indeed contain a carditis patients show minimal symp-
pool of progenitors, which represent the cellular source both for toms only or are entirely asymptomatic
accumulation of differentiated monocytes during the acute inflammatory (McCarthy et al. 2000). Heart-infiltrating
phase and for transforming growth factor-β-mediated myocardial fibrosis cells include granulocytes, monocytes,
macrophages, dendritic cells, mast cells,
during the lat