复方丹参滴丸治疗不稳定性心绞痛的临床研究
田焱林李翠霞黄石有色总医院内2科
地址湖北黄石新下陆有色总医院内2科
电话:0714-5397681
邮编:435005 E-mail:tyl00008@
【摘要】目的:观察复方丹参滴丸治疗不稳定性心绞痛(UA)的临床疗效。方法:分别观察复方丹参滴丸组(36例)、对照组(30例)治疗前后的心绞痛发作频率,硝酸甘油用量,静息心电图,血压,心率及心肌耗氧量的变化。结果:复方丹参滴丸组在减少心绞痛发作,降低硝酸甘油用量,改善异常心电图方面优于对照组(P<),心肌耗氧量也明显减少(P<)。结论:复方丹参滴丸治疗UA效果肯定,副作用小,值得临床推广应用。
关键词复方丹参滴丸不稳定性绞痛心肌耗氧量
Clinical Study of Fufang Danshen Diwan Treatment of Patients with Unstable Angina
Objective: To observe the clinical efficacy of Fufang Danshen Diwan in treating patients with unstable angina(UA)Methods: Frequency of angina events ,consumed doses of nitrates, heart rate ,blood pressure, rest electrocardiogram(ECG)and myocardial oxygen consumption were observed before and after drug therapy in Fufang Danshen Diwan group(36cases)and control group (30cases)respectively .Results: The Fufang Danshen Diwan
group not only showed more effective than in control group in reducing frequency of angina events and consumed doses of 1
nitrates and improving abnormal rest ECG, but also appeared to be preferable to the control group in reducing myocardial oxygen consumption and increasing exercise duration(P<)Conclusion: Fufang Danshen Diwan is a safe and effective drug in treating patients with UA.
【key words】Fufang Danshen Diwan, unstable angina,myocardial oxygen consumption
复方丹参滴丸是豆科植物野葛的干燥根中提取的单体——异黄酮化合物。临床及基础研究证明该药具有扩张冠状动脉及脑血管,降低血液粘滞度及改善微循环等药
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