脾脏射频消融术治疗肝硬化性脾功能亢进症.pdf

临床肝胆病杂志 2011年第27卷第2期 119
专论
脾脏射频消融术治疗肝硬化性
脾功能亢进症
刘全达,周宁新
(解放军第二炮兵总医院肝胆胃肠病研究所,北京 100088)
摘要: 大部分肝硬化患者合并有脾功能亢进症,表现为脾脏肿大、一种或几种血细胞(主要是血小板、白细胞)减少。
传统治疗措施存在较大的局限性和/或并发症。作者在国际上率先开展的脾脏射频消融治疗脾亢的新型微创措施,本文从脾
脏射频消融治疗脾亢的工作原理、治疗入路、安全性、临床疗效、提高安全性和疗效的联合脾脏射频消融的多手段治疗模
式等多个角度,总结了作者近10年的实验和临床实践经验。本文可为其他单位开展该项新技术提供一定的参考价值。
关键词: 脾功能亢进;肝硬化;导管消融术
中图分类号: 文献标识码: A 文章编号: 1001-5256(2011)02-0119-04
Treatment of radiofrequency ablation for cirrhotic hypersplenism
LIU Quan-da, ZHOU Ning-xin. (Institute of Hepatobiliary Gastrointestinal Disease, PLA Second Artillery General Hospital, Beijing
100088, China)
Abstract: A large proportion of patients with liver plicated with hypersplenism, shows the sign of splenomegaly,
anemia, thrombocytopenia, leucopenia, or pancytopenia. Conventional treatments have some limitations plication. The
authors firstly applied a minimally invasive procedure of radiofrequency ablation for hypersplenism used worldwide. The article
reviewed the experimental and clinical experiences in radiofrequency ablation for hypersplenism in terms of principle, access,
safety, efficacy, and RFA-based multimodalities strategy during recent 10 years. It may provide reference for others to develop a new
technology.
Key words: hypersplenism; liver cirrhosis; catheter ablation
脾功能亢进症(脾亢)是肝硬化性门静脉高功能、促进肝脏再生和延缓肝硬化进程,也能
压症患者常见的临床综合征之一,表现为脾脏降低食管胃曲张静脉出血的风险,具有较好的
肿