宫颈肿瘤治疗.ppt

Cervical Tumor 宫颈肿瘤   Xin LUObstetrics and Gynecology Hospital  Fudan University
Contents
CIN
HPV
Histology
Pathology
Diagnosis
Treatment
Cervical Cancer
General information
Pathology
Spread pattern
FIGO staging
Clinical signs
Diagnosis and differential diagnosis
Principle for treatment
Prevention
Key words
Human Papillomavirus (HPV)
Radical Hysterectomy (RH)
Radiotherapy (RT)
Chemotherapy (CT)
Neoadjuvant chemotherapy
(NACT)
Concurrent chemo-radiotherapy
(CCCR)
Radical Trachelectomy
人乳头瘤状病毒
广泛全子宫切除术
放射治疗
化学治疗
新辅助化疗
同步放化疗
宫颈根治术
Female Reproductive Anatomy
Transformation Zone
Cervical Cancer 子宫颈癌
World report:
Account for 1/3 female malignancies
New cases: 529 800
Death: 275 100
85% developing country
The 4th mon cause of death from malignancy in women.
流行病学
新发病例数
死亡病例数
Cervical cancer progression
HPV infection

CINs 10-15yrs

Carcinoma in situ

Cervical cancer
Cervical tumorigenesis
Progression
Host immunity
Environmental factors
ics:
oncogene E6, E7
tumor suppresor gnen p53, Rb
Regression
High Risk Factors
HR-HPV
Use of oral contraceptives
Smoking
Multiple sexual partners
History of herpes infection
History of STD