鸦胆子油乳注射液联合顺铂胸腔灌注治疗肺癌所致恶性胸腔积液的疗效观察.doc

鸦胆子油乳注射液联合顺铂胸腔灌注治疗肺癌所致恶性胸腔积液的疗效观察.doc英文摘要
drenching 1 days ago and after drenching a week, review blood routine examination
and observe the drainage of pleural effusion, effusion color variation and a chest pain,
fever, cough, nausea and vomiting and bone marrow depression and other adverse
reactions. At 4 weeks after the end of treatment were observed after treatment efficacy
evaluation, evaluation of the quality of life and toxicity evalua of the clinical
observation of brucea javanica oil injection and cisplatin infused in thorax in
treatment of malignant pleural effusion caused by lung cancer. All datas use
software to statistical analysis.
Results
1 objective response rate: Complete remission in 15 cases in the observation
group and partial remission in 11 cases, stability in 3 cases, progress 1 .control group
complete remission in 8 cases, partial remission 10 cases, stable in 8 cases, progress
in 4 objective response rate of the observation group and the control group,
are % and 60% respectively, observation group was significantly higher than the
control group, the difference between the two groups is statistically significant
(P<).
2 centers for disease control rate:The disease control rates of treatment and
control groups are % and %, And the difference between the two groups is
statistically significant (P<).
3 quality of life: The observation group and the control group continued to
improve the quality of life patients ≥ 21 days are % and %. the observation
group is significantly better than the control group, the difference between the two
groups was statistically significant (P<).
4 toxicity: The observation group and the control group during the treatment
period, and no obvious plications such as hemorrhage, pneumothorax, and
no deaths. The major toxic reactions between the observation group and the control
group are chest pain and fever, and rashes, nausea and vomiting, they are inⅠ~Ⅱ,
no Ⅲ~Ⅳ of toxic reactions and