CT脑灌注成像在短暂性脑缺血发作中的应用.doc

CT脑灌注成像在短暂性脑缺血发作中的应用
(作者:___________单位: ___________邮编: ___________)
作者:康孝理许俊萍姜丙全赵玉铁刘四化
【摘要】目的探讨CT灌注成像(CTP)对短暂性脑缺血发作(TIA)的诊断价值及相关病因的检查方法。方法 35例TIA患者均在发病24h内行CT和CTP检查,在发病12~72h行头颅MRI及MRA检查,分别就CT检出的病灶和MRI检出的病灶与CTP检查的结果相比较。结果 CT共检出21个病灶,头颅MRI共检出26个病灶,CTP共检出38个病灶,其中11个病灶表现为相对血流量(RF)降低,CT脑灌注的最大峰值时间(PT)与平均通过时间(MTT)延长。6个病灶RF与对比区域相比无明显降低,其MTT略延长,PT时间明显延长。结论 CTP对TIA的诊断具有超早性和定位价值。从而能及时追查病因,避免大面积脑梗死的发生,可做为TIA的常规检查项目。
【关键词】体层摄影术,X线计算机;短暂性脑缺血;脑灌注;局部血流
Objective To explore the diagnosis value of CT perfusion imaging on In 35 TIA patients, CT and CTP were performed in 24 hours after TIA onset, MRI and MRA were performed in 12~72h. The detection efficiencies of these imaging methods were Twentyone, twentysix and thirtyeight ischemic lesions were detected by CT, MRI and CTP, respectively. Eleven lesions detected by CTP showed relatively decreased blood flow and prolonged peak time (PT) and mean transit time (MTT); Six lesions showed significantly prolonged MTT and slightly prolonged PT, but no change in blood CTP might be a valuable tool in detecting ischemic lesions of TIA. It could be routinely applied in the early diagnosis of TIA.

【Key words】 Computerized tomography; Transient ischemic attack; Cerebral perfusion; Regional blood flow

短暂性脑缺血发作(TIA)是由于局灶性脑或视网膜缺血所致的短暂发作的神经功能障碍,典型的临床症状持续时间一般在1h之内,且没有急性梗死的证据。现将35例TIA患者CT脑灌注成像资料分析如下。