腔内成型术治疗犬顽固性脑血管痉挛
作者:韩军良,万琪,张学昕,李力,郭以川,张魏
【关键词】脑血管痉挛
【Abstract】 AIM: To investigate the efficacy of treating experimental refractory cerebral vasospasm (rCVS) with percutaneous tansluminal angioplasty (PTA) or intraartery papaverine infusion (IAP) plus PTA. METHODS: 45 adult mongrel dogs were sacrificed and 40 were used in experimental group and 5 in the control. Artery spasm was induced by twotime blood injection into brain cisterns. In the experiment group, PTA or IAP plus PTA was chosen by the status of vessels. In the control group, papaverine was given through intraveins. RESULTS: Basilar arteries of all the dogs were constricted after the twotime blood injection. In the experimental group, 20 dogs were treated by PTA but only 18 eeded. 13 dogs in the experimental group were treated by IAP plus PTA therapy, but only 3 of them eeded. In the control group, the spastic arteries of all dogs showed no improvement following the therapy. When reexamined 20 days later, the 21 canines treated by either PTA or IAP plus PTA all had normal angiograph, while those of the control group and those who had not essfully had PTA or IAP plus PTA in experiment group had little change. CONCLUSION: PTA is effective trea
tment of cerebral vasospasm.
【Kewords】 cerebral vasospasm; angioplasty; animal
【摘要】目的: 探讨单纯球囊或罂粟碱联合球囊介入动脉腔内治疗顽固性脑血管痉挛的可行性和效果. 方法: 成年杂种犬45只,脑血管痉挛模型采用枕大池两次注血法. 实验组40只,根
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