(1)Stableangina(2)Unstableangina(3):animbalancebetweenthemyocardialoxygensupplyanddemandmajordeterminantsofmyocardialoxygenconsumption:myocardialbasicmetabolismheartratecontractilitywalltensionejectiontimebloodpressure(peripheralresistance)(1)Deceasemyocardialoxygenconsumption(2)Increasemyocardialbloodandoxygensupply(3)antiplatelet、:Nitroglycerin(硝酸甘油),isosorbidedinitrate(硝酸异山梨酯)isosorbidemononitrate(单硝酸异山梨酯) guanylylcyclasecGMPcGMPdependentproteinkinaseintracellularCa2+(1)decreasemyocardiacoxygenconsumptiondilatevenousdecreasebloodreturningtoheartdecreaseventricularend-diastolicvolumeandpressure(largedose)dilatearterialdecreaseperipheralresistancedecreaseafterload(2)increasebloodsupplytoischemiaarea(3)redistributionofcoronarybloodflow(4)Inhibiteofplateletaggregation,,(1)alltypesofangina(2)acutemyocardiainfarction(3),flushing,throbbingheadache,orthostatichypotension,methemoglobinemia
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